作者回复: 比较复杂，根据资源类型、隐私策略、各浏览器的设计哲学等而定，例如chrome官方文档曾经这么描述：“Chrome employs two caches — an on-disk cache and a very fast in-memory cache. The lifetime of an in-memory cache is attached to the lifetime of a render process, which roughly corresponds to a tab. Requests that are answered from the in-memory cache are invisible to the web request API. If a request handler changes its behavior (for example, the behavior according to which requests are blocked), a simple page refresh might not respect this changed behavior. To make sure the behavior change goes through, call handlerBehaviorChanged() to flush the in-memory cache. But don't do it often; flushing the cache is a very expensive operation. You don't need to call handlerBehaviorChanged() after registering or unregistering an event listener.”